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Australasian Biometrics and New Zealand Statistical Association Joint Conference 2001
December 10-13, 2001
Park Royal Hotel
Christchurch, New Zealand

Organizers
David Baird, Dave Saville, Harold Henderson, Peter Johnstone, Marco Reale, Irene Hudson, Julian Visch, Roger Littlejohn

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Probabilities for genetic data from pedigrees
by
Sharon Browning
Department of Statistics, North Carolina State University

Probabilities of genotype data from related individuals are used in gene-mapping studies to assess evidence for linkage, and in inferring relationships between individuals in various settings. Calculation methods generally assume simple models for genetic processes, however with increasing density of genetic markers on chromosomes better models are needed. Exact calculation of probabilities is often possible with simple models, while more realistic models generally require Monte Carlo approaches. In this talk I will give some background on pedigree genetics, discuss modeling issues and describe an importance sampling method.

Date received: November 7, 2001

Copyright © 2001 by the author(s). The author(s) of this document and the organizers of the conference have granted their consent to include this abstract in Atlas Conferences Inc. Document # caic-26.