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First International Workshop in Sequential Methodologies (IWSM 2007)
July 22-25, 2007
Auburn University
Auburn, AL, U.S.A.

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A two-stage procedure for selecting the best diagnostic biomarker with dichotomous outcomes
by
Aiyi Liu
National Institutes of Health
Coauthors: Chengqing Wu and Kai F. Yu

Consider the problem of selecting the best diagnostic biomarker from a number of candidate markers. Assume that the biomarkers yield dichotomous outcomes, and the one with highest classification rate is claimed to be the best marker. The probability of correct selection for this procedure depends on a number of nuisance parameters from a mutinomial distribution. We investigate the performance of a two-stage procedure that controls the probability of correct selection at the desired level.

Date received: April 18, 2007

Copyright © 2007 by the author(s). The author(s) of this document and the organizers of the conference have granted their consent to include this abstract in Atlas Conferences Inc. Document # cauc-79.