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A Model for Gene Activation
by
Seth F. Oppenheimer
Mississippi State University
Coauthors: Stephen Pruett &
Ruping Fan
Experimental work has shown that exposure to certain classes of pesticides can effect cytokine production. Indeed, the level of transcription factors within the cell is affected by exposure to these exogenous compounds and we hypothesize that this is the mechanism that leads to changes in cytokine production. We propose a model in the form of a system of ordinary differential equations which tracks gene activation and the consequent production of the cytokine IL-6.
This is joint work with Stephen Pruett of the Department Basic Science in the College of Veterinary Medicine of Mississippi State University and Ruping Fan of Department of Cellular Biology and Anatomy, Louisiana State University Health Sciences Center. SFO was supported by National Institutes of Health grants DHHS/NIH 5 P20 RR17661 and NIH ES 11278
Date received: September 5, 2007
Copyright © 2007 by the author(s). The author(s) of this document and the organizers of the conference have granted their consent to include this abstract in Atlas Conferences Inc. Document # cavp-06.