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Society for Mathematical Biology Conference
July 30 - August 2, 2008
Centre for Mathematical Medicine, Fields Institute
Toronto, Canada

Organizers
Organizing Committee: S.Sivaloganathan-Chair(Waterloo), M.Kohandel (Waterloo), I.Pressman(Carleton), F.Skinner(Toronto Western Research Inst.), H. Zhu(York)

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A Coalescent Theory Analysis of the Population Structure Statistic Fst
by
Sivan Rottenstreich
Georgetown University

Populations are often divided into subpopulations. Fst is a statistic used to experimentally test for population subdivision. We consider a stochastic model of evolution for subdivided populations. We analyze Fst under different scaling limits for parameters of this model. We show that the distribution of Fst depends on mutation rate and we characterize the distribution in the different scaling limits. Our results are the first to describe the distribution of Fst and demonstrate its dependence on mutation rate. We use a coalescent theory approach to derive our results.

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Date received: February 2, 2008

Copyright © 2008 by the author(s). The author(s) of this document and the organizers of the conference have granted their consent to include this abstract in Atlas Conferences Inc. Document # cawd-08.