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Society for Mathematical Biology Conference
July 30 - August 2, 2008
Centre for Mathematical Medicine, Fields Institute
Toronto, Canada

Organizers
Organizing Committee: S.Sivaloganathan-Chair(Waterloo), M.Kohandel (Waterloo), I.Pressman(Carleton), F.Skinner(Toronto Western Research Inst.), H. Zhu(York)

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Detecting spill-over: A dynamical systems modeling approach to glutamatergic synaptic signaling
by
Emily Stone
Dept. of Mathematical Sciences, University of Montana-Missoula
Coauthors: Greg Leary, Katie Hoffman, Micheal Kavanaugh, Dept. of Biomedical and Pharmaceutical Science, University of Montana-Missoula

The connectivity of neurons in the hippocampus depends in part on whether neurotransmitter from one release site can leak out and activate receptors in another synapse or extrasynaptic patch. The existence of such "spill-over" is under debate in the neuroscience community, since direct measurements of neurotranmitter in such detail cannot, as of yet, be made. Experimental evidence of spillover is thus indirect, and should be sifted through as many different filters as possible. In this talk I will present the contributions of dynamical systems modeling to this effort.

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Date received: April 11, 2008


Copyright © 2008 by the author(s). The author(s) of this document and the organizers of the conference have granted their consent to include this abstract in Atlas Conferences Inc. Document # cawd-24.